Outpatient Opioid Dispensing Patterns for SC Medicaid Children 1–36 Months Old.

Objectives: We sought to identify the most common diagnostic categories linked to dispensed opioid prescriptions among children 1–36 months old and changes in patterns over the years 2000 to 2017. Methods: This study used South Carolina's Medicaid claims data of pediatric dispensed outpatient opioid prescriptions between 2000 and 2017. The major opioid-related diagnostic category (indication) for each prescription was identified using visit primary diagnoses and the Clinical Classification System (AHRQ-CCS) software. The variables of interest were the rate of opioid prescriptions per 1,000 visits for each diagnostic category and the relative percentage of opioid prescriptions assigned to each category compared to all categories. Results: Six major diagnostic categories were identified; Diseases of the respiratory system (RESP), Congenital anomalies (CONG), Injury (INJURY), Diseases of the nervous system and sense organs (NEURO), Diseases of the digestive system (GI), and Diseases of the genitourinary system (GU). The overall rate of dispensed opioid prescriptions per category declined significantly for four diagnostic categories throughout the study period, RESP by 15.13, INJURY by 8.49, NEURO by 7.33, and GI by 5.93. Two categories increased during the same time, CONG (by 9.47) and GU (by 6.98). RESP was the most prevalent category linked to a dispensed opioid prescription within 2010–2012 (almost 25%) but CONG was the most prevalent by 2014 (17.77%). Conclusions for practice: Among Medicaid children 1–36 months old, annual dispensed opioid prescription rates declined for most major diagnostic categories (RESP, INJURY, NEURO, and GI). Future studies should explore alternatives to current opioid dispensing practices for GU and CONG cases. Significance: Eventhough opioid is a high-risk medication for children, it is continued to be prescribed to pediatric population. A little is known about the diagnoses associated with opioid prescribing among children 1–36 months old and their trends. This study demonstrates that opioid prescriptions linked to respiratory diagnosis have become less prevalent, surpassed by opioids prescribed for surgical conditions. [ABSTRACT FROM AUTHOR]