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Metastasis of endometrial cancer to breast: A rare case.

Authors :
Erdoğan, Özgür
Balci, Mücahit Furkan
Özgüzer, Alp
Özdaş, Emel
Görgülü, Gökşen
Sanci, Muzaffer
Source :
Journal of Obstetrics & Gynaecology Research. May2023, Vol. 49 Issue 5, p1452-1455. 4p.
Publication Year :
2023

Abstract

Only 2% of all breast cancers are metastatic, making them extremely uncommon. They are frequently mistaken for a primary breast tumor. Although it has been observed, metastatic spread from primary uterine cancers is extremely uncommon. In the literature, our case represents the fourth endometroid adenocarcinoma metastasis from the uterus. Clinical, pathological, and immunohistochemical examination and management of metastatic endometrioid adenocarcinoma of the uterus' extragenital organ were described in this 69‐year‐old patient's case. Immunohistochemical analysis was performed on a breast biopsy taken from the patient who underwent therapy and discovered a breast mass two years later. Metastatic endometrial adenocarcinoma was diagnosed with negative signs pointing to mammaglobin, GCDFP‐15 and GATA3 breasts and markers indicating endometroid adenocarcinomas such as p53, PAX8 and VIMENTIN support. As a result, a thorough clinical history is needed, with special attention to diagnoses of concurrent or prior malignancies, along with clinical examination, appropriate radiological evaluation, and immunohistochemistry. This is necessary to prevent unnecessary surgery, to provide appropriate systemic treatment, to ensure correct diagnosis, and to manage treatment. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13418076
Volume :
49
Issue :
5
Database :
Academic Search Index
Journal :
Journal of Obstetrics & Gynaecology Research
Publication Type :
Academic Journal
Accession number :
163413147
Full Text :
https://doi.org/10.1111/jog.15621