The value of ACTN1 in the diagnosis of cutaneous squamous cell carcinoma: A continuation study.

If left untreated, Bowen's disease may progress to invasive CSCC with the incidence of 3%-5%.[8] The exact mechanisms by which Bowen's disease progresses to CSCC are complicated and merits more attention. Keywords: ACTN1; biomarkers; Bowen's disease; cutaneous squamous cell carcinoma EN ACTN1 biomarkers Bowen's disease cutaneous squamous cell carcinoma 1 4 4 05/03/23 20230401 NES 230401 Cutaneous squamous cell carcinoma (CSCC) originates from epidermal keratinocytes or adnexal structures, including eccrine glands and (or) pilosebaceous units. According to our results, we only found the expression levels of SERPINB1 and ACTN1 in serum of patients with CSCC were significantly higher than that of Bowen's disease ( I p i < 0.05). [Extracted from the article]