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Coupling of protein condensates to ordered lipid domains determines functional membrane organization.

Authors :
Hong-Yin Wang
Sze Ham Chan
Dey, Simli
Castello-Serrano, Ivan
Rosen, Michael K.
Ditlev, Jonathon A.
Levental, Kandice R.
Levental, Ilya
Source :
Science Advances. 4/28/2023, Vol. 9 Issue 17, p1-12. 12p.
Publication Year :
2023

Abstract

The article focuses on the biophysical and functional coupling between membrane lipid domains and cytoplasmic biomolecular condensates. Topics discussed include the relationship between lipid self-organization and condensate formation, specifically focusing on the role of linker of activation of T cells (LAT) in coupling ordered membrane domains and protein condensation.

Details

Language :
English
ISSN :
23752548
Volume :
9
Issue :
17
Database :
Academic Search Index
Journal :
Science Advances
Publication Type :
Academic Journal
Accession number :
163358419
Full Text :
https://doi.org/10.1126/sciadv.adf6205