Does Topiramate Decrease the Efficacy of Oral Contraceptives?

The article focuses on if topiramate, a migraine and other headache drug, reduces the efficacy of oral contraceptives. It reports the findings of a retrospective cohort study that compared the rates of accidental pregnancies among women taking combined oral contraceptives with topiramate versus other headache therapies, and the findings revealed no significant difference in contraception failure rates among the two groups.