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Structural characterization of water-soluble polysaccharides from Sophora flavescens Ait. and their anti-inflammatory activities based on NO release.
- Source :
-
Journal of Carbohydrate Chemistry . 2022, Vol. 41 Issue 7-9, p405-423. 19p. - Publication Year :
- 2022
-
Abstract
- Sophora flavescens Ait. is a medicinal herb traditionally used to treat inflammatory diseases. In this study, four polysaccharides, SFNP-1, SFNP-2, SFAP-1, and SFAP-2, were isolated from S. flavescens. Both SFNP-1 and SFNP-2 were (1→4)-linked glucans. SFAP-1 and SFAP-2 were identified as pectin-type polysaccharides containing mainly a homo-galacturanan backbone (as shown). NO release inhibition test revealed that the major polysaccharides, SFAP-1 and SFAP-2, did not have a significant anti-inflammatory effect. This result suggests that the anti-inflammatory effect of S. flavescens may not depend on its polysaccharides. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 07328303
- Volume :
- 41
- Issue :
- 7-9
- Database :
- Academic Search Index
- Journal :
- Journal of Carbohydrate Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 163317369
- Full Text :
- https://doi.org/10.1080/07328303.2023.2174551