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Primary Lymphoproliferative Lung Diseases: Imaging and Multidisciplinary Approach.

Authors :
Gozzi, Luca
Cozzi, Diletta
Cavigli, Edoardo
Moroni, Chiara
Giannessi, Caterina
Zantonelli, Giulia
Smorchkova, Olga
Ruzga, Ron
Danti, Ginevra
Bertelli, Elena
Luzzi, Valentina
Pasini, Valeria
Miele, Vittorio
Source :
Diagnostics (2075-4418). Apr2023, Vol. 13 Issue 7, p1360. 14p.
Publication Year :
2023

Abstract

Lymphoproliferative lung diseases are a heterogeneous group of disorders characterized by primary or secondary involvement of the lung. Primary pulmonary lymphomas are the most common type, representing 0.5–1% of all primary malignancies of the lung. The radiological presentation is often heterogeneous and non-specific: consolidations, masses, and nodules are the most common findings, followed by ground-glass opacities and interstitial involvement, more common in secondary lung lymphomas. These findings usually show a prevalent perilymphatic spread along bronchovascular bundles, without a prevalence in the upper or lower lung lobes. An ancillary sign, such as a "halo sign", "reverse halo sign", air bronchogram, or CT angiogram sign, may be present and can help rule out a differential diagnosis. Since a wide spectrum of pulmonary parenchymal diseases may mimic lymphoma, a correct clinical evaluation and a multidisciplinary approach are mandatory. In this sense, despite High-Resolution Computer Tomography (HRCT) representing the gold standard, a tissue sample is needed for a certain and definitive diagnosis. Cryobiopsy is a relatively new technique that permits the obtaining of a larger amount of tissue without significant artifacts, and is less invasive and more precise than surgical biopsy. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20754418
Volume :
13
Issue :
7
Database :
Academic Search Index
Journal :
Diagnostics (2075-4418)
Publication Type :
Academic Journal
Accession number :
163040333
Full Text :
https://doi.org/10.3390/diagnostics13071360