A one-pot access to 2-(N-substituted Amino)-Quinones or 3-indolyl-Quinones from naphthol/hydroquinone.

A sequential one-pot approach towards 2-(N- substituted amino)-1,4-quinones or 3-indolyl-quinones from naphthol/hydroquinone with amines or indoles, such as various (hetero)aromatic amine and aliphatic amine, has been developed. The reaction proceeds through oxidation of naphthol/hydroquinone with the CuBr 2 or (NH 4) 2 S 2 O 8 oxidant. This reaction provides efficient access to the biologically important and synthetically useful 2-amino-quinones and 3-indolyl-quinones with good yields under mild conditions. The present protocol is simple, practical and shows good functional group tolerance. To create your abstract, type over the instructions in the template box below. Fonts or abstract dimensions should not be changed or altered. [Display omitted]. [ABSTRACT FROM AUTHOR]