Site-Directed Chemical Cross-Linking Demonstrates that Helix IV Is Close to Helices VII and XI in...

Highlights a study which explored the N-terminal six transmembrane helices and the C-terminal transmembrane helices of the lactose permease, containing a single-Cys residue. Methodology; Cross-linking permease with paired Cys residues in helices IV and VII; Ligand-induced changes in cross-linking.