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Oncological outcomes of large gastrointestinal stromal tumors treated by laparoscopic resection.

Authors :
Lin, Sheng-Chieh
Yen, Hung-Hsuan
Lee, Po-Chu
Lai, I-Rue
Source :
Surgical Endoscopy & Other Interventional Techniques. Mar2023, Vol. 37 Issue 3, p2021-2028. 8p.
Publication Year :
2023

Abstract

Background: The resection of large gastric gastrointestinal stromal tumors (GISTs) by laparoscopic has been controversial. Extending from our prior study, the long-term oncological outcome of laparoscopic resection of large (5–8 cm) gastric GISTs was reported. Methods: From 2002 to 2018, a consecutive 66 patients with gastric GISTs of 5-8 cm were treated at National Taiwan University Hospital. Among them, 30 patients received open surgery, and 36 received laparoscopic surgery. The clinicopathological data, peri-operative and oncological outcomes were compared between groups. Results: The clinical demographics including sex, age, BMI, tumor locations and ratio of wedge resection were similar between groups. The mean tumor size was 6.0 ± 0.83 cm versus 6.3 ± 1.07 cm (Open vs. Laparoscopic, p = 0.3). The operation time, blood loss, and post-operative complications, were also similar. The mean hospital stay was shorter in the laparoscopic group (8.8 ± 2.5 days) than in the open group (12.0 ± 8.9 days), though not significantly different. The median follow-up time was 108 ± 58 months (97 ± 50 in laparoscopic group; 122 ± 64 in open group). All except three patients remain disease-free. One in the open group and two in the laparoscopic group had recurrence of tumor, and they were stable of disease under Imatinib treatment. Eight patients died in non-GIST causes during follow-up. The 5-year recurrence-free survival were 100% for the open and 94.2% for the laparoscopic group (p = 0.2). Conclusion: Our data showed that laparoscopic surgery for gastric GIST between 5 and 8 cm was safe and oncologically feasible. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
18666817
Volume :
37
Issue :
3
Database :
Academic Search Index
Journal :
Surgical Endoscopy & Other Interventional Techniques
Publication Type :
Academic Journal
Accession number :
162470718
Full Text :
https://doi.org/10.1007/s00464-022-09693-x