A case of fixed drug eruption from cetirizine with cross‐reaction to levocetirizine and hydroxyzine.

Case report, cetirizine, cutaneous adverse drug reaction, fixed drug eruption, hydroxyzine, levocetirizine, patch tests Keywords: case report; cetirizine; cutaneous adverse drug reaction; fixed drug eruption; hydroxyzine; levocetirizine; patch tests EN case report cetirizine cutaneous adverse drug reaction fixed drug eruption hydroxyzine levocetirizine patch tests 318 319 2 03/15/23 20230401 NES 230401 Fixed drug eruption (FDE) is a cutaneous adverse drug reaction most frequently caused by non-steroidal anti-inflammatory drugs (NSAIDs), antibiotics, anticonvulsants, or paracetamol.[1] Uncommonly, cetirizine and other H1 antihistamines have also been implicated in FDE.[[2]] We report a case of cetirizine-induced FDE with cross-reaction with other piperazine derivatives confirmed by patch test. 2 Cravo M, Gonçalo M, Figueiredo A. Fixed drug eruption to cetirizine with positive lesional patch tests to the three piperazine derivatives. [Extracted from the article]