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Application of CRISPR/Cas9 Technology in Cancer Treatment: A Future Direction.
- Source :
-
Current Oncology . Feb2023, Vol. 30 Issue 2, p1954-1976. 23p. 3 Diagrams, 5 Charts. - Publication Year :
- 2023
-
Abstract
- Gene editing, especially with clustered regularly interspaced short palindromic repeats associated protein 9 (CRISPR-Cas9), has advanced gene function science. Gene editing's rapid advancement has increased its medical/clinical value. Due to its great specificity and efficiency, CRISPR/Cas9 can accurately and swiftly screen the whole genome. This simplifies disease-specific gene therapy. To study tumor origins, development, and metastasis, CRISPR/Cas9 can change genomes. In recent years, tumor treatment research has increasingly employed this method. CRISPR/Cas9 can treat cancer by removing genes or correcting mutations. Numerous preliminary tumor treatment studies have been conducted in relevant fields. CRISPR/Cas9 may treat gene-level tumors. CRISPR/Cas9-based personalized and targeted medicines may shape tumor treatment. This review examines CRISPR/Cas9 for tumor therapy research, which will be helpful in providing references for future studies on the pathogenesis of malignancy and its treatment. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 11980052
- Volume :
- 30
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Current Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 162118306
- Full Text :
- https://doi.org/10.3390/curroncol30020152