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Role of Methylprednisolone for COVID-19 Patients Admitted to a Tertiary Care Hospital.
- Source :
-
Pakistan Armed Forces Medical Journal . Dec2022, Vol. 72 Issue 6, p2041-2044. 4p. - Publication Year :
- 2022
-
Abstract
- Objective: To determine the role of Methylprednisolone in managing COVID-19 patients. Study Design: Cross-sectional study. Place and Duration of Study: Pakistan Emirates Military Hospital (PEMH), Rawalpindi Pakistan, from Jan to Feb 2021. Methodology: This study was carried out at the Department of Medicine. Medical records of all moderate, severe and critical COVID-19 patients admitted and receiving Methylprednisolone were reviewed. Methylprednisolone was used in all patients at doses 0.-2 mg per kg. Results: A total of 200 cases were included. The most common presenting symptoms were cough (77.5%), fever (67.5%) and shortness of breath (63.5%). Most patients (85%) presented within the first week of their illness. One or more comorbidities were present in 75% of patients. Most common being hypertension in 70(35%) and diabetes mellitus in 63(31.5%). Complications seen in the study were Cytokine release storm 92(46%) and acute respiratory distress syndrome 44(22%). The median time for initiation of corticosteroid therapy was 4 hours (range 1-96 hours). Overall survival (OS) in the study was 83.5%. OS for patients with moderate, severe and critical diseases was 97.8%, 86.2% and 62%, respectively (p<0.001). Conclusion: Corticosteroids are useful in COVID-19-admitted patients and provide excellent survival outcomes. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00309648
- Volume :
- 72
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Pakistan Armed Forces Medical Journal
- Publication Type :
- Academic Journal
- Accession number :
- 161946980
- Full Text :
- https://doi.org/10.51253/pafmj.v72i6.6602