EBNEO Commentary: Nasal high‐flow therapy during neonatal endotracheal intubation.

Successful first-attempt intubation, regardless of physiologic instability, was 68.5% vs. 54.3% in the high-flow and standard-care groups, respectively, which are comparable to previous studies.[3] In subgroup analysis, regardless of gestation (<= or 28 weeks) and premedication use status (yes or no), the high-flow group had higher success rates at first intubation than the standard-care group. It lacks long-term outcomes, posing the question of the longer-term benefit of a successful first attempt at intubation without physiological instability. In summary, the study showed that using high-flow during non-emergency neonatal endotracheal intubations increased success at the first attempt but sans physiological instability, with greater benefit seen in inexperienced operators. [Extracted from the article]