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A nonlinear HCV model in deterministic and randomly fluctuating environments.

Authors :
Qi, Ke
Liu, Zhijun
Wang, Lianwen
Wang, Qinglong
Source :
Mathematical Methods in the Applied Sciences. Mar2023, Vol. 46 Issue 4, p4644-4662. 19p.
Publication Year :
2023

Abstract

Two novel deterministic and stochastic nonlinear hepatitis C virus (HCV) models with nonlinear incidence rates as βSpE,βSpI$$ \beta {S}^pE,\beta {S}^pI $$, and βSpCq$$ \beta {S}^p{C}^q $$, containing acute and chronic infections, are developed, and an endeavor to understand their dynamics has been accomplished. For the former model, both the existence of unique equilibria and the sharp sufficient conditions of globally stable equilibria under different cases are established. Whereafter, the efforts taken to detect the asymptotic behaviors around equilibria, the existence of ergodic stationary distribution, and stochastic extinction of the latter model have been supplemented with meticulous theoretical proofs. At last, several numerical examples and discussions are illustrated to sustain and visualize our theoretical results. Compared and analyzed the numerical and theoretical results, we can find that the noise can influence the dynamics of disease and turn the disease from persistence to extinction. Moreover, several control measures are suggested based on our study. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
*HEPATITIS C virus

Details

Language :
English
ISSN :
01704214
Volume :
46
Issue :
4
Database :
Academic Search Index
Journal :
Mathematical Methods in the Applied Sciences
Publication Type :
Academic Journal
Accession number :
161743369
Full Text :
https://doi.org/10.1002/mma.8792