Back to Search
Start Over
Ocular manifestations in IgA nephropathy.
- Source :
-
Survey of Ophthalmology . Mar2023, Vol. 68 Issue 2, p290-307. 18p. - Publication Year :
- 2023
-
Abstract
- Immunoglobulin A nephropathy (IgAN) is a rare but important systemic disease with or without ocular manifestations. We describe 4 cases of IgAN presenting with scleritis and review the various ocular manifestations in patients with IgAN. We found 55 cases with ocular manifestations in patients with prior or newly-diagnosed IgAN described in 38 publications. The most common ocular manifestations of IgAN were episcleritis (23.6%), scleritis (16.4%), hypertensive retinopathy or retinal vasculopathy (20.0%), and uveitis (14.5%). The median age at presentation was 36.5 years, with 54.5% female patients. 61.8% had history of IgAN prior to ocular involvement, while 29.1% had ocular presentations as the first manifestation of IgAN. The majority received systemic corticosteroids and/or immunosuppressants. Additionally, we report 4 women with anterior scleritis and previous diagnosis of IgAN. All 4 were treated with topical and systemic corticosteroids. Three out of 4 patients had no recurrence for at least 1 year since the first presentation. IgAN is a rare but important systemic association to be considered in ocular inflammatory conditions. Timely recognition and comanagement of the disease with nephrologist could reduce disease morbidity. [ABSTRACT FROM AUTHOR]
- Subjects :
- *OCULAR manifestations of general diseases
*SCLERITIS
*WOMEN patients
*UVEITIS
Subjects
Details
- Language :
- English
- ISSN :
- 00396257
- Volume :
- 68
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Survey of Ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 161739241
- Full Text :
- https://doi.org/10.1016/j.survophthal.2022.09.004