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Emerging hemostatic materials for non-compressible hemorrhage control.
- Source :
-
National Science Review . Nov2022, Vol. 9 Issue 11, p1-17. 17p. - Publication Year :
- 2022
-
Abstract
- Non-compressible hemorrhage control is a big challenge in both civilian life and the battlefield, causing a majority of deaths among all traumatic injury mortalities. Unexpected non-compressible bleeding not only happens in pre-hospital situations but also leads to a high risk of death during surgical processes throughout in-hospital treatment. Hemostatic materials for pre-hospital treatment or surgical procedures for non-compressible hemorrhage control have drawn more and more attention in recent years and several commercialized products have been developed. However, these products have all shown non-negligible limitations and researchers are focusing on developing more effective hemostatic materials for non-compressible hemorrhage control. Different hemostatic strategies (physical, chemical and biological) have been proposed and different forms (sponges/foams, sealants/adhesives, microparticles/powders and platelet mimics) of hemostatic materials have been developed based on these strategies. A summary of the requirements, state-of-the-art studies and commercial products of non-compressible hemorrhage-control materials is provided in this review with particular attention on the advantages and limitations of their emerging forms, to give a clear understanding of the progress that has been made in this area and the promising directions for future generations. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HEMORRHAGE
*OPERATIVE surgery
*SEALING compounds
*FOAM
*ADHESIVES
Subjects
Details
- Language :
- English
- ISSN :
- 20955138
- Volume :
- 9
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- National Science Review
- Publication Type :
- Academic Journal
- Accession number :
- 161559835
- Full Text :
- https://doi.org/10.1093/nsr/nwac162