Back to Search
Start Over
RIPK1 blocks T cell senescence mediated by RIPK3 and caspase-8.
- Source :
-
Science Advances . 1/25/2023, Vol. 9 Issue 4, p1-17. 17p. - Publication Year :
- 2023
-
Abstract
- The article discusses a research study which found that T cell–specific Receptor-interacting protein kinase 1 (RIPK1) deficiency leads to the premature senescence in T cells, which is accompanied by the senescent-associated secretory phenotype (SASP). The study also clarified the function of RIPK3 and caspase-8 in inducing CD4 T cell senescence, which is modulated by environmental signals.
Details
- Language :
- English
- ISSN :
- 23752548
- Volume :
- 9
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Science Advances
- Publication Type :
- Academic Journal
- Accession number :
- 161510577
- Full Text :
- https://doi.org/10.1126/sciadv.add6097