Back to Search
Start Over
Monocyte to high density lipoprotein ratio in patients with acute kidney injury after cardiac surgery.
- Source :
-
Perfusion . Jan2023, Vol. 38 Issue 1, p172-177. 6p. - Publication Year :
- 2023
-
Abstract
- Background: The Monocyte to high density lipoprotein ratio (MHR) has been postulated as a novel parameter associated with adverse renal and cardiovascular outcomes. In this study we investigated the association of MHR with cardiac surgery-associated acute kidney injury (CSA-AKI). Methods: In this retrospective study, we analyzed the data pertaining to 1505 patients undergoing cardiopulmonary bypass (CPB) surgery. The CSA-AKI, which was defined using Kidney Disease Improving Global Outcomes criteria. Concurrently, a retrospective scan of patient files was conducted and information relevant to nephropathy such as the level of their serum creatinine (SCr), Blood urea nitrogen (BUN), uric acid (UA), serum cystatin C (Cys-C), total cholesterol (TC), triglycerides (TG), glucose and MHR, ejection fraction, CPB duration time, and other indicators. Results: About 1505 patients were studied of whom 195 developed AKI. MHR was significantly higher in the AKI patients (p = 0.001). In multivariate logistic regression analysis, MHR, UA, Cys-C, age, glucose, and history of chronic kidney disease or hypertension were independently correlated with CSA-AKI. Conclusions: As a laboratory index, the elevated MHR is convenient, independent, and a useful predictor for CSA-AKI. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CARDIAC surgery
*CONFIDENCE intervals
*MULTIPLE regression analysis
*RETROSPECTIVE studies
*FISHER exact test
*RISK assessment
*T-test (Statistics)
*RESEARCH funding
*CHI-squared test
*DESCRIPTIVE statistics
*HIGH density lipoproteins
*DATA analysis software
*ODDS ratio
*RECEIVER operating characteristic curves
*ACUTE kidney failure
*MONOCYTES
*DISEASE risk factors
Subjects
Details
- Language :
- English
- ISSN :
- 02676591
- Volume :
- 38
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Perfusion
- Publication Type :
- Academic Journal
- Accession number :
- 161309031
- Full Text :
- https://doi.org/10.1177/02676591211041945