Back to Search
Start Over
The protective effect of erinacine A–enriched Hericium erinaceus mycelium ethanol extract on oxidative Stress–Induced neurotoxicity in cell and Drosophila models of spinocerebellar ataxia type 3.
- Source :
-
Free Radical Biology & Medicine . Feb2023, Vol. 195, p1-12. 12p. - Publication Year :
- 2023
-
Abstract
- [Display omitted] • HEME diminishes BH induced apoptosis in SK-N-SH-MJD78 cells. • HEME decreases mutant ataxin-3 protein aggregation in tBH treated SCA3 cell model. • HEME modulates p53 and NF-κB activation in tBH treated SK-N-SH-MJD78 cells. • HEME increases survival and climbing ability in tBH treated SCA3 Flies. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 08915849
- Volume :
- 195
- Database :
- Academic Search Index
- Journal :
- Free Radical Biology & Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 161306045
- Full Text :
- https://doi.org/10.1016/j.freeradbiomed.2022.12.005