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Viral prevalence by gestational age and season in a large neonatal cord blood cohort.
- Source :
-
Journal of Maternal-Fetal & Neonatal Medicine . Dec2022, Vol. 35 Issue 25, p8482-8487. 6p. - Publication Year :
- 2022
-
Abstract
- Objective: To investigate viral prevalence in a large neonatal cohort and determine the impact on pregnancy and birth outcomes. Study design: We prospectively collected 1044 neonatal samples from remnant neonatal cord blood RPR samples. We performed qRT-PCR/qPCR reactions for: adenovirus, anellovirus (alphatorquevirus and betatorquevirus), cytomegalovirus (CMV), Epstein-Barr virus (EBV), enterovirus, human herpesvirus 6 (HHV6), parechovirus, and parvovirus B19. Result: Overall viral prevalence was 5.6% with 58 positive samples. Alphatorquevirus (2%) and HHV6 (1.2%) were the two most prevalent viruses detected. Viral detection was most common in samples collected in the fall (September-November) and least common in those collected in winter (December-February). There was no statistical difference detected in viral prevalence or viral load by gestational age, preterm delivery, pre-eclampsia or chorioamnionitis. Conclusion: While there is seasonal variation in viral prevalence in neonatal cord blood samples, individual virus presence does not seem to effect pregnancy or birth outcomes. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14767058
- Volume :
- 35
- Issue :
- 25
- Database :
- Academic Search Index
- Journal :
- Journal of Maternal-Fetal & Neonatal Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 161126786
- Full Text :
- https://doi.org/10.1080/14767058.2021.1983537