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Rumex acetosella L. (Kuzukulağı)'nın In vitro Antiradikal, Antimikrobiyal, Antikanser ve Fitokimyasal Özellikleri.

Authors :
Keser, Fatma
Karatepe, Mustafa
Keser, Serhat
Tekin, Suat
Türkoğlu, İsmail
Kayğılı, Ömer
Demir, Ersin
Yılmaz, Ökkeş
Sandal, Süleyman
Kırbağ, Sevda
Source :
Bilecik Seyh Edebali University Journal of Science / Bilecik Şeyh Edebali Üniversitesi Sosyal Bilimler Dergisi. 2022, Vol. 9 Issue 2, p683-692. 10p.
Publication Year :
2022

Abstract

R. acetosella is a perennial herbaceous plant in the Polygonaceae family and is consumed as a vegetable among the people in Turkey. In this study, antimicrobial (Escherichia coli, Bacillus megaterium, Bacillus subtilis, Proteus vulgaris, Pseudomonas aeruginosa, Listeria monocytogenes, Klebsiella pneumoniae, Staphylococcus aureus bacteria and Candida albicans yeast-fungi), antiradical (against to DPPH, ABTS and OH radicals), anticancer (against to human prostate cancer (PC-3), human colon cancer (HCT-116), human ovarian cancer (A2780) and human breast cancer (MCF-7) cell lines) and phytochemical properties (lipid-soluble vitamins, fatty acids, flavonoids, phenolic acids, phytosterols, total phenolic compounds, total flavonoid, and total proanthocyanidins) of ethanol, water and methanol extracts of R. acetosella aerial parts were investigated. According to our results, it was determined that R. acetosella extracts have higher activity than the BHT in scavenging tests of ABTS, DPPH and OH radicals. It has also been understood that this plant has high antimicrobial activity and phytochemical content and effective anticancer activities against to PC-3 human prostate cancer cell lines. Also the presented study is the first study on the in vitro anticancer activity of R. acetosella extracts. [ABSTRACT FROM AUTHOR]

Details

Language :
Turkish
ISSN :
24587575
Volume :
9
Issue :
2
Database :
Academic Search Index
Journal :
Bilecik Seyh Edebali University Journal of Science / Bilecik Şeyh Edebali Üniversitesi Sosyal Bilimler Dergisi
Publication Type :
Academic Journal
Accession number :
161110676
Full Text :
https://doi.org/10.35193/bseufbd.994208