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AIE -active TPA modified Schiff base for successive sensing of Cu2+ and His via an on–off–on method and its application in bioimaging.
- Source :
-
Dalton Transactions: An International Journal of Inorganic Chemistry . 1/14/2023, Vol. 52 Issue 2, p434-443. 10p. - Publication Year :
- 2023
-
Abstract
- In this article, a novel triphenylamine-modified salicylaldehyde Schiff base 2-(((4-(diphenylamino)phenyl)imino)methyl)-4-(pyridine-4-yl)phenol (HL) was synthesized and structurally characterized. HL possessed D–π-A structure and exhibited typical AIE property in THF/H2O. It was applied to selectively recognize Cu2+ through an on–off mode in THF/H2O (1/9, v/v), and the fluorescence attenuation was attributed to a paramagnetic quenching effect of Cu2+ together with the abatement of HL aggregates. Hence, the detection limit achieved was as low as 1.32 × 10−7 M. The spectroscopic and ESI-HRMS results revealed a 1 : 2 complexation ratio of Cu2+ with HL. The mechanism for sensing Cu2+ was further confirmed by performing DFT calculations. Owing to the large affinity between Cu2+ and His, the resultant CuL2 system was further used to detect His via the off–on method based on the displacement of ligands. The detection limit for His reached 5.14 × 10−8 M. Furthermore, HL was available to prepare handy indicator papers for the on-site recognition of Cu2+ and His. Confocal fluorescent imaging demonstrated that HL could sequentially respond to intracellular Cu2+ and His. [ABSTRACT FROM AUTHOR]
- Subjects :
- *SCHIFF bases
*TRIPHENYLAMINE
*DETECTION limit
*PHENOL
*SENSES
Subjects
Details
- Language :
- English
- ISSN :
- 14779226
- Volume :
- 52
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Dalton Transactions: An International Journal of Inorganic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 161098715
- Full Text :
- https://doi.org/10.1039/d2dt03457c