Index lesion detection in multifocal prostate cancer: Simplified PI-RADS biparametric MRI vs PI-RADS v2.1 multiparametric MRI.

• Detection of index lesion (IL) by MRI is crucial to perform targeted biopsy, to monitor the progression of the PCa and to guide the focal therapy. • In prostate with multifocal lesions, the IL can be the smallest markedly hypointense lesion vs the largest with moderate hypointensity on ADC maps. • Sensitivity in the detection of IL was 79.6–83% and 93.2–94.9% with the PI-RADS v2.1 and S-PI-RADS criteria, respectively [ABSTRACT FROM AUTHOR]