CLINICAL AND ANATOMOPATHOLOGICAL CORRELATIONS IN GLIOBLASTOMA MULTIFORME.

Described in the literature as a characteristic feature of adulthood, glioblastoma is the most common malignant brain tumour of this age group, accounting for less than 20% of all intracranial tumours and about 80% of all astrocytic neoplasms. Risk factors involved in the development of this type of tumour include certain genetic disorders such as Li-Fraumeni syndrome (an autosomal dominant syndrome, fortunately extremely rare but predisposing to various forms of cancer), Turcot syndrome or neurofibromatosis. On the other hand, radiotherapy in the past also seems to be a factor in the development of glioblastoma. It is predominantly found in the cerebral hemispheres, is rarely found in the brainstem and occurs exceptionally in the cerebellum. Scientific studies conducted globally have shown a male:female ratio of 1.26 in the US and 1.28 in Europe. The peak incidence is between 40 and 70 years of age, but cases have also been observed, less frequently, in children with predominantly brainstem involvement. In what follows I would like to present the case of a 68-yearold patient, admitted with the suspicion of a tumour formation with right temporo-parietal location, which was found to be a glioblastoma multiforme after CT, anatomopathological and immunohistochemical examinations. [ABSTRACT FROM AUTHOR]