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Mechanisms of DNA opening revealed in AAA+ transcription complex structures.

Authors :
Fuzhou Ye
Forson Gao
Xiaojiao Liu
Martin Buck
Xiaodong Zhang
Source :
Science Advances. 12/21/2022, Vol. 8 Issue 51, p1-12. 12p.
Publication Year :
2022

Abstract

The article presents a study which explores mechanisms of DNA opening revealed in AAA+ transcription complex structures. It mentions that gene transcription as carried out by RNA polymerase (RNAP) and requires the conversion of the initial closed promoter complex, where DNA is double stranded, to a transcription-competent open promoter complex, where DNA is opened up.

Details

Language :
English
ISSN :
23752548
Volume :
8
Issue :
51
Database :
Academic Search Index
Journal :
Science Advances
Publication Type :
Academic Journal
Accession number :
160927302
Full Text :
https://doi.org/10.1126/sciadv.add3479