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Cardiac Involvement in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.
- Source :
-
Journal of Clinical Medicine . Dec2022, Vol. 11 Issue 23, p6983. 15p. - Publication Year :
- 2022
-
Abstract
- Cardiac involvement of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is recognized extremely rarely. In addition, most CLL/SLL patients with heart infiltration are asymptomatic. In this review, we present the results of a literature search for English language articles concerning CLL/SLL or Richter transformation with symptomatic cardiac involvement. In total, 18 well-described cases with CLL/SLL and heart infiltration were identified. Only three patients were not diagnosed with CLL/SLL before the cardiac manifestation. In other patients, cardiac CLL/SLL was diagnosed between 5 months and 20 years from CLL/SLL diagnosis. All patients in these series had a diagnosis of secondary cardiac CLL/SLL. In addition, we identified four reported cases with Richter transformation in the heart. The treatment of patients with CLL/SLL and cardiac infiltration is variable and depends on the previous history and clinical characteristics of heart infiltration. In addition, no recommendations exist on how to treat patients with CLL/SLL and cardiac involvement. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CHRONIC lymphocytic leukemia
*RICHTER syndrome
*LYMPHOMAS
Subjects
Details
- Language :
- English
- ISSN :
- 20770383
- Volume :
- 11
- Issue :
- 23
- Database :
- Academic Search Index
- Journal :
- Journal of Clinical Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 160738455
- Full Text :
- https://doi.org/10.3390/jcm11236983