Determination of EkoSonic Endovascular System Treatment According to Patient Characteristics in High-risk Pulmonary Embolism Patients.

Objectives: Pulmonary embolism (PE) is the third most common cause of cardiovascular death. The EkoSonic Endovascular System is one of the treatments for thrombus. In this study, it was aimed to investigate the results of ECOS treatment and the effects of personal characteristics such as age, gender, and clinical history on the effectiveness and safety of treatment in patients with high or moderately high-risk PE. Methods: In this study, 51 patients who underwent ECOS with the diagnosis of medium-high-risk PE were analyzed retrospectively. Arterial blood gas oxygen saturation, partial oxygen pressure (PaO2 ) values, RV diameters, pulmonary arterial pressure (PAPs), and tricuspid regurgitation in echocardiography and Qanadli Score in computed tomography were recorded in all patients before and after the procedure. In addition, PE and deep vein thrombosis localization, complete blood count, hemoglobin, hematocrit, platelet count, urea, creatinine values, minor and major bleeding, recurrent venous thromboem bolism, and presence of complications were evaluated. All the data obtained were compared in male and female groups, in the over 65 age group and in groups classified according to the history of the underlying disease. Results: In all patients, the mean of saturation and PaO2 after the procedure was higher than before the procedure, the averages of hemoglobin, hematocrit, creatine, right ventricular (RV) diameter, PAP, and Qanad value were found to be lower than before the procedure (p<0.05). The RV diameter difference before and after the procedure was found to be higher in patients over 65 years of age than in patients under 65 years of age (p<0.05). Considering the gender distribution of ten patients with complications, 1 (10%) of the patients were male and 9 (90%) were female. Conclusion: This study shows that ECOS is an effective treatment option in patients with high-risk PE. [ABSTRACT FROM AUTHOR]