Deleterious effects of COVID-2019 Lockdown on health responses in adolescents with obesity: longitudinal study.

This longitudinal and observational study investigated the consequences of the coronavirus disease 2019 lockdown on health-related physical fitness and biochemical responses in 16 overweight or obese male adolescents (aged 12.6±1.8 years). The anthropometry, body composition, physical fitness tests, and measures of blood biomarkers (fasting blood glucose, total cholesterol [TC], lowdensity lipoprotein cholesterol [LDL-c], triglycerides [TG], aspartate aminotransferase [AST], and alanine aminotransferase [ALT]) were evaluated before and after 8 months of lockdown. The results showed increased body weight, fat-free mass, and waist and hip circumference (p<0.05) after 8 months. Maximum isometric handgrip strength and flexibility increased, while muscle endurance decreased (p<0.05). Fasting blood glucose, TC, LDL-c, TG, TG/glucose, AST, ALT, TG/HDL-c, CT/HDL-c, and LDL/HDL increased (p<0.05), while the HDL-c levels decreased significantly (p<0.05). Therefore, eight months of social isolation promoted harmful effects on adolescents' morphological parameters and physical fitness. However, the small sample size prevents the generalization of these findings. [ABSTRACT FROM AUTHOR]