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Multicatalysis protocol enables direct and versatile enantioselective reductive transformations of secondary amides.
- Source :
-
Science Advances . 11/25/2022, Vol. 8 Issue 47, p1-11. 11p. - Publication Year :
- 2022
-
Abstract
- The article presents a study on a catalytic asymmetric reductive/deoxygenative alkynylation of secondary amides. Topics discussed include the scope of the reaction and chemoselectivity, alkynes and functional group tolerance of the rection, the extension to N-benxylamides, and synthetic applications of the reaction.
Details
- Language :
- English
- ISSN :
- 23752548
- Volume :
- 8
- Issue :
- 47
- Database :
- Academic Search Index
- Journal :
- Science Advances
- Publication Type :
- Academic Journal
- Accession number :
- 160414603
- Full Text :
- https://doi.org/10.1126/sciadv.ade3431