新生儿骶尾部畸胎瘤的产前诊断与多学科协作模式治疗.

Objective To explore the prenatal diagnosis and multidisciplinary treatment (MDT) of neonatal sacrococcygeal teratoma (SCT). Methods From April 2015 to January 2021, clinical data were retrospectively reviewed for 35 children of neonatal SCT. The MDT team consisted of neonatal surgeons, prenatal physicians, ultrasonic specialists, obstetricians, neonatologists and pathologists. According to the tumor diameter, 34 children were divided into giant teratoma group ( tumor diameter > 10 cm, 13 cases) and ordinary teratoma group (tumor diameter ~10 cm,21 cases). The differences in gender, gestational age, birth type, birth weight, length of hospital stay, postoperative complications and tumor properties were compared between the two groups. Results Thirty-three SCT cases were identified by MDT, and one case was detected after birth. All cases were timely operated. Postoperative pathology revealed mature teratoma (n = 29,85. 3%) and immature teratoma (n = 5, 14.7%). There were no significant differences in gestational age, mode of delivery, birth weight, wound healing and average length of hospital stay between the two groups ( P > 0. 05). Wound dehiscence and infection were two major postoperative complications. The post-discharge follow-up period was 6 to 36 months. There was no recurrence or obvious rectal dysfunction. Conclusion Prenatal diagnosis can timely and effectively detect SCT children. And MDT may improve the prognosis of neonatal SCT. [ABSTRACT FROM AUTHOR]