消化系统肿瘤心脏转移的临床特征分析.

Objective To investigate the clinical features of patients with cardiac metastases from digestive system tumors. Methods This retrospective study collected and analyzed the medical records of patients with cardiac metastases from digestive system tumors who received treatments in the Cancer Hospital, Chinese Academy of Medical Sciences between January 1999 and January 2021. Kaplan-Meier method was used for survival analysis. Results A total of 19 patients were identified. The primary tumors were esophageal squamous cell carcinoma ( n = 7), gastric or gastroesophageal junction adenocarcinoma (n = 6), hepatobiliary cancers ( n = 3 ) and colorectal cancers ( n = 3 ). 16 patients had pericardial metastases, 2 patients had right atrium metastases, and 1 patient had left ventricle metastasis. The most common symptom was dyspnea, which was present in 8 cases. 7 patients received locoregional treatment, while 11 patients underwent systemic therapies. The median overall survival from diagnosis of primary cancer was 31.4 months, and the median overall survival time from diagnosis of cardiac metastasis was 4.7 months. Conclusion Cardiac metastasis from digestive system tumors is associated with low incidence and a poor prognosis. Systemic treatment remains the cornerstone of management, while novel anti-tumor drugs may improve therapeutic efficacy. [ABSTRACT FROM AUTHOR]