CFR-PEEK Pedicle Screw Instrumentation for Spinal Neoplasms: A Single Center Experience on Safety and Efficacy.

Simple Summary: Advances in screening methods and new therapeutic strategies have lead to a continuous decline in cancer death rates, especially over the last ten years. As a consequence, the number of patients with spinal metastases is increasing. In modern oncological treatment surgery followed by postoperative radiotherapy for spinal metastases has gained a decisive role. For spinal stabilization, pedicle screws and rods are used. They used to be made of titanium or cobalt–chrome alloys. Recently, carbon-fiber-reinforced (CFR) polyethyl-ether-ether-ketone (PEEK) was introduced as a new material reducing artifacts on imaging and showing less perturbation effects on photon radiation. The aim of this study is to report on the safety and efficacy of CFR-PEEK pedicle screw systems for spinal neoplasms in a large cohort of consecutive patients. We could show that implant-related complications, such as intraoperative screw breakage and screw loosening, were rare. So, we conclude that CFR-PEEK is a safe and efficient alternative to titanium for oncological spinal instrumentation. (1) Background: Surgery for spinal metastases has gained a decisive role in modern oncological treatment. Recently, carbon-fiber-reinforced (CFR) polyethyl-ether-ether-ketone (PEEK) pedicle screw systems were introduced, reducing artifacts on imaging and showing less perturbation effects on photon radiation. Preliminary clinical experience with CFR-PEEK implants for spinal metastases exists. The aim of this monocentric study is to report on the safety and efficacy of CFR-PEEK pedicle screw systems for spinal neoplasms in a large cohort of consecutive patients. (2) Methods: We retrospectively analyzed prospectively the collected data of consecutive patients being operated on from 1 August 2015 to 31 October 2021 using a CFR-PEEK pedicle screw system for posterior stabilization because of spinal metastases or primary bone tumors of the spine. (3) Results: We included 321 patients of a mean age of 65 ± 13 years. On average, 5 ± 2 levels were instrumented. Anterior reconstruction was performed in 121 (37.7%) patients. Intraoperative complications were documented in 30 (9.3%) patients. Revision surgery for postoperative complications was necessary in 55 (17.1%) patients. Implant-related complications, such as intraoperative screw breakage (3.4%) and screw loosening (2.2%), were rare. (4) Conclusions: CFR-PEEK is a safe and efficient alternative to titanium for oncological spinal instrumentation, with low complication and revision rates in routine use and with the advantage of its radiolucency. [ABSTRACT FROM AUTHOR]