Baricitinib as an effective treatment for lichen planopilaris.

Lichen planopilaris (LPP), an uncommon inflammatory scalp disorder resulting in scarring of alopecia on the scalp, was challenging in treatment due to poor responses to available therapies.1 In this letter, we reported a case of LPP improved with oral baricitinib. The histopathology of an alopecia patch at low magnification, Hematoxylin-Eosin stain 10× (B), and at high magnification, Hematoxylin-Eosin stain 40× (C). gl GLO:ETZ/01nov22:dth15882-fig-0002.jpg PHOTO (COLOR): 2 The changes in dermoscopy examination during the treatment of baricitinib: before treatment (A), after treatment with a dosage of 4 mg daily for 3 months (B), and continuous treatment with a dosage of 2 mg daily for 6 months (C). Physical examination showed erythematous alopecia patches on the scalp's parietal areas, with perifollicular erythema and follicular hyperkeratosis at the margins of expanding alopecic patches (Figure 1A). [Extracted from the article]