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Green synthesis of guar gum/Ag nanoparticles and their role in peel-off gel for enhanced antibacterial efficiency and optimization using RSM.
- Source :
-
International Journal of Biological Macromolecules . Nov2022, Vol. 221, p665-678. 14p. - Publication Year :
- 2022
-
Abstract
- Polysaccharide-based guar gum (GG) biopolymer is used via a hydrothermal process to synthesize silver nanoparticles. The GG biopolymer act as a reducing and stabilizing agent. Moreover, GG was used for preparing peel-off masks to provide the desired consistency of formulation and synthesis of nanoparticles as an antibacterial agent. This work presents the novel GG/Ag nanoparticles peel-off gel and evaluates the antibacterial efficiency. The synthesized Ag-nanoparticles analyzed by UV–spectroscopy reflect a prominent peak at 413 nm. The size and distribution of nanoparticles were examined by TEM images obtained from the 6 to 18 nm range. We demonstrate the efficiency of peel-off facial gel as an antibacterial and preservative-free cosmetic product at different temperature ranges. The RSM study was used for parameter optimization of peel-off gel for extrudability, spreadability, and drying time by employing a CCD. The results show that the optimized GG, PVA, and ethanol concentration were 3.47, 8.30, and 5.80 w/w%, respectively, with 0.02 w/w% Ag nanoparticles. The peel-off gel antibacterial activity against Escherichia coli (11 ± 0.1 mm), Staphylococcus aureus (10 ± 0.3 mm), and Propionibacterium acnes (11 ± 0.3 mm). The peel-off gel was prepared from natural ingredients; due to this, it is non-toxic for human skin. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01418130
- Volume :
- 221
- Database :
- Academic Search Index
- Journal :
- International Journal of Biological Macromolecules
- Publication Type :
- Academic Journal
- Accession number :
- 159857569
- Full Text :
- https://doi.org/10.1016/j.ijbiomac.2022.09.036