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Curcumin and blood lipid levels: an updated systematic review and meta-analysis of randomised clinical trials.

Authors :
Saeedi, Farhad
Farkhondeh, Tahereh
Roshanravan, Babak
Amirabadizadeh, Alireza
Ashrafizadeh, Milad
Samarghandian, Saeed
Source :
Archives of Physiology & Biochemistry. Dec2022, Vol. 128 Issue 6, p1493-1502. 10p.
Publication Year :
2022

Abstract

The present study was designed to indicate the protective effects of curcumin on dyslipidemia. Main databases were searched to recognise randomised clinical trials evaluating the effect of curcumin on blood lipid profiles. The pooled odds ratio with a 95% confidence interval (CI) was used to evaluate the effect of curcumin on blood lipid parameters. HDL-C levels in the curcumin group were 0.04-fold lower than placebo (95% CI:−0.36–0.29; Z = 0.23; p =.82). LDL-C levels in the curcumin group reduced by 0.17 versus the placebo group (95% CI: −0.43–0.09; Z = 1.27; p =.2). TC levels in the curcumin group were 0.21 lower versus the placebo group (95% CI: −0.55–0.13; Z = 1.22; p =.22). TG level in the curcumin group were 0.05 lower versus the placebo (95% CI: −0.20–0.11; Z = 0.58; p =.56). This study suggests that curcumin may reduce blood lipid levels and can be used as a hypolipidemic agent. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13813455
Volume :
128
Issue :
6
Database :
Academic Search Index
Journal :
Archives of Physiology & Biochemistry
Publication Type :
Academic Journal
Accession number :
159811903
Full Text :
https://doi.org/10.1080/13813455.2020.1779309