Serum albumin/hyaluronic acid nanoconjugate: Evaluation of concentration-dependent structural changes to form an efficient drug carrier particle.

Authors :: Varga, Norbert
Seres, László
Kovács, Nikolett Alexandra
Turcsányi, Árpád
Juhász, Ádám
Csapó, Edit
Source :: International Journal of Biological Macromolecules. Nov2022, Vol. 220, p1523-1531. 9p.
Publication Year :: 2022
Abstract: • Electrostatic and hydrophobic forces exist in serum albumin/hyaluronic acid system • The charge compensation process of macromolecules is affected by HyA concentration • Preparation of HSA/HyA particles can be strongly controlled by initial conditions • HSA/HyA nanocarrier facilitates better solubility and controlled dissolution of D3 [ABSTRACT FROM AUTHOR]

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