SARS-CoV-2 PCR Pozitif Hastalarda Bakteriyel Enfeksiyonlar ve Antibiyotik Direnci.

Background: In this study, it was aimed to determine the distribution and antibiotic resistance rates of bacteria isolated from endotracheal aspirate (ETA), blood and catheter samples taken from COVID-19 patients admitted Adana City Training and Research Hospital. Materials and Methods: Between April 1, 2020 and March 31, 2021, 254 patients PCR positive patients were included in the study. Blood, catheter and respiratory tract culture growths and antibiotic susceptibility test results were retrospectively analyzed from the microbiology laboratory database. Results: 433 bacterial growths were detected in clinical samples taken from 254 COVID-19 PCR positive patients. Among the bacterial agents, Acinetobacter baumannii (25.17%; n =109) was the most common pathogens, followed by Escherichia coli (5.54% n =24) and Klebsiella pneumoniae (5.31%; n =23). While imipenem and meropenem resistance rates for A. baumannii were 86.8% and 85.9%, ertapenem and meropenem resistance rates for K. pneumoniae and E. coli were 83.3%, 75%, and 12.5%, 4,1%, respectively. I n this study, 15 o f 21 S.aureus strains were found to be MRSA (Methicillin-resistant S.aureus) (71,4%). Conclusions: Avoiding unnecessary antibiotic use in COVID-19 patients is critical to prevent resistance development and increase culture sensitivity. [ABSTRACT FROM AUTHOR]