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A mesoscale agent based modeling framework for flow-mediated infection transmission in indoor occupied spaces.

Authors :
Mukherjee, Debanjan
Wadhwa, Gauri
Source :
Computer Methods in Applied Mechanics & Engineering. Nov2022:Part A, Vol. 401, pN.PAG-N.PAG. 1p.
Publication Year :
2022

Abstract

The ongoing Covid-19 pandemic, and its associated public health and socioeconomic burden, has reaffirmed the necessity for a comprehensive understanding of flow-mediated infection transmission in occupied indoor spaces. This is an inherently multiscale problem, and suitable investigation approaches that can enable evidence-based decision-making for infection control strategies, interventions, and policies; will need to account for flow physics, and occupant behavior. Here, we present a mesoscale infection transmission model for human occupied indoor spaces, by integrating an agent-based human interaction model with a flow physics model for respiratory droplet dynamics and transport. We outline the mathematical and algorithmic details of the modeling framework, and demonstrate its validity using two simple simulation scenarios that verify each of the major sub-models. We then present a detailed case-study of infection transmission in a model indoor space with 60 human occupants; using a systematic set of simulations representing various flow scenarios. Data from the simulations illustrate the utility and efficacy of the devised mesoscale model in resolving flow-mediated infection transmission; and elucidate key trends in infection transmission dynamics amongst the human occupants. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00457825
Volume :
401
Database :
Academic Search Index
Journal :
Computer Methods in Applied Mechanics & Engineering
Publication Type :
Academic Journal
Accession number :
159475812
Full Text :
https://doi.org/10.1016/j.cma.2022.115485