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Risk factors for aneurysm rupture among Kazakhs: findings from a national tertiary.
- Source :
-
BMC Neurology . 9/20/2022, Vol. 22 Issue 1, p1-7. 7p. - Publication Year :
- 2022
-
Abstract
- <bold>Background: </bold>Rupture of intracranial aneurysms (RIA) leads to subarachnoid hemorrhage (SAH) with severe consequences. Although risks for RIA are established, the results vary between ethnic groups and were never studied in Kazakhstan. This study aimed to establish the risk factors of RIA in the Kazakh population.  METHODS: Retrospective analysis of 762 patients with single IAs, who attended the neurosurgical center from 2008 until 2018, was conducted. Demographic characteristics, such as age, sex, smoking status, and hypertension were considered. Descriptive and bivariate analyses were performed. A multivariable logistic regression model was built to identify factors correlated with RIA.<bold>Results: </bold>The mean age of participants was 48.49 ± 0.44 years old. The majority (68.37%) of IAs have ruptured. Of the ruptured aneurysms, 43.76% were < 6 mm, and 38.39% were located on the anterior cerebral and anterior communicating arteries (ACA). Logistic regression model indicates younger age group (16-40 years), smoking, having stage 3 hypertension, smaller IA size and its location on ACA increase the odds of rupture.<bold>Conclusions: </bold>This study has revealed that younger, smoking patients with stage 3 arterial hypertension are at higher risk for RIA. Small aneurysms (< 6 mm) and location on ACA had increased odds of rupture, while larger aneurysms on internal carotid arteries had lower odds. [ABSTRACT FROM AUTHOR]
- Subjects :
- *INTERNAL carotid artery
*ANEURYSMS
*RUPTURED aneurysms
*ANTERIOR cerebral artery
*BIVARIATE analysis
*INTRACRANIAL aneurysm ruptures
*ANEURYSM surgery
*HYPERTENSION epidemiology
*INTRACRANIAL aneurysm surgery
*HYPERTENSION
*KAZAKHS
*RETROSPECTIVE studies
*INTRACRANIAL aneurysms
*DISEASE complications
Subjects
Details
- Language :
- English
- ISSN :
- 14712377
- Volume :
- 22
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- BMC Neurology
- Publication Type :
- Academic Journal
- Accession number :
- 159212621
- Full Text :
- https://doi.org/10.1186/s12883-022-02901-0