Voľná nádorová DNA u pacientov s klasickým Hodgkinovým lymfómom.

Circulating tumour DNA (ctDNA) is a type of extracellular circulating cell-free DNA (ccfDNA, cfDNA) released into the blood of cancer patients by apoptosis and necrosis of tumour cells. It represents an alternative bio-marker for the qualitative and quantitative analysis that may together with PET/CT imaging refine the assessment of treatment response in patients with Hodgkin lymphoma. As a dynamic parameter, it could be applied for refining dia-gnosis, initial screening for mutations and patient risk stratification. During treatment and at its the end, it could be used to evaluate treatment efficacy and may also be useful for further monitoring and relapse prediction. [ABSTRACT FROM AUTHOR]