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Syphilis Testing and Diagnosis Among People With Human Immunodeficiency Virus (HIV) Engaged in Care at 4 US Clinical Sites, 2014-2018.
- Source :
-
Clinical Infectious Diseases . Aug2022, Vol. 75 Issue 3, p483-492. 10p. - Publication Year :
- 2022
-
Abstract
- Background Despite rising rates of syphilis among people with human immunodeficiency virus (HIV; PWH) in the United States, there is no optimal syphilis screening frequency or prioritization. Methods We reviewed records of all PWH in care between 1 January 2014 and 16 November 2018 from 4 sites in the Centers for AIDS Research Network of Integrated Clinical Systems Cohort (CNICS; N = 8455). We calculated rates of syphilis testing and incident syphilis and used Cox proportional hazards models modified for recurrent events to examine demographic and clinical predictors of testing and diagnosis. Results Participants contributed 29 568 person-years of follow-up. The rate of syphilis testing was 118 tests per 100 person-years (95% confidence interval [CI]: 117–119). The rate of incident syphilis was 4.7 cases per 100 person-years (95% CI: 4.5–5.0). Syphilis diagnosis rates were highest among younger cisgender men who have sex with men and transgender women, Hispanic individuals, people who inject drugs, and those with detectable HIV RNA, rectal infections, and hepatitis C. Conclusions We identified PWH who may benefit from more frequent syphilis testing and interventions for syphilis prevention. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DIAGNOSIS of syphilis
*SYPHILIS epidemiology
*HIV-positive persons
*CONFIDENCE intervals
*INTRAVENOUS drug abuse
*TRANS women
*HISPANIC Americans
*LOG-rank test
*MULTIVARIATE analysis
*MEDICAL screening
*ACQUISITION of data
*DISEASE incidence
*RACE
*HEPATITIS C
*SEX distribution
*MEDICAL records
*DESCRIPTIVE statistics
*SURVIVAL analysis (Biometry)
*KAPLAN-Meier estimator
*MEN who have sex with men
*DATA analysis software
*STATISTICAL models
*PROPORTIONAL hazards models
*LONGITUDINAL method
*CISGENDER people
Subjects
Details
- Language :
- English
- ISSN :
- 10584838
- Volume :
- 75
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Clinical Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 158846307
- Full Text :
- https://doi.org/10.1093/cid/ciab944