IL‐13: An essential cDC2s partner to maintain skin homeostasis.

Keywords: CD11b; conventional dendritic cells; IL-13; skin EN CD11b conventional dendritic cells IL-13 skin 2869 2871 3 09/02/22 20220901 NES 220901 Abbreviations cDCs conventional DCs DCs dendritic cells IL interleukin ILCs innate lymphoid cells Th T helper TSLP thymic stromal lymphopoietin Interleukin (IL)-13 and IL-4 are potent cytokines critical for the development of T-cell-mediated humoral responses due to their capacity to recruit and activate IgE-producing B cells, enhancing the allergic response. IL-13: An essential cDC2s partner to maintain skin homeostasis Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote TH2 and inhibit TH17 cell polarization. [Extracted from the article]