1,1-Difunctionalization of α ‑Carbonyl Sulfur Ylides with Thiosulfonates: Synthesis of β -Keto Thiosulfones.

1,1-Difunctionalization of α ‑carbonyl sulfur ylides and thiosulfonates under simple conditions is disclosed. In this protocol, two new C–S bonds are constructed in a one-step reaction. A series of aliphatic and aromatic β -keto thiosulfones were obtained in moderate to good yields. This reaction probably proceeds through sulfur ylide-involved- nucleophilic substitution of an ion pair within a solvent cage. [ABSTRACT FROM AUTHOR]