半量睫状体光凝术对青光眼患者生活质量 及血清Endothelin-1水平的影响.

Objective: To explore the effect of half volume ciliary body photocoagulation on the quality of life and serum endothelin-1 (ET-1) level of glaucoma patients. Methods: 80 patients (80 eyes) with glaucoma treated in our hospital from April 2018 to April 2021 were selected as the research object, and they were divided into the research group (n=40, treated with half volume ciliary body photocoagulation) and the control group according to the difference of operation methods (n=40, trabeculectomy), observe and record the postoperative anterior chamber reaction and corneal edema of the two groups, analyze the changes of preoperative and postoperative intraocular pressure, visual acuity and serum ET-1 level of the two groups, record the operation success rate and postoperative complications of the two groups, and compare the differences between the two groups. Results: (1) There was no difference in anterior chamber reaction and corneal endothelial edema between the study group and the control group at 1 d and 7 d after operation (P>0.05); (2) In the study group, 20 cases were completely successful, 19 cases were relatively successful, and the total success rate was 97.50 %. In the control group, 15 cases were completely successful, 22 cases were relatively successful, and the total success rate was 87.50 %. There was no difference in the operation success rate between the two groups (P>0.05); (3) At 7 d, 1 month and 3 months after operation, the intraocular pressure in the study group was lower than that in the control group (P<0.05); (4) At 1 month after operation, there was no difference in the level of ET-1 between the two groups (P>0.05), but the quality of life in the study group was higher than that in the control group (P<0.05); (5) There was no difference in the incidence of complications between the two groups (P>0.05). Conclusion: Half volume ciliary body photocoagulation has a better therapeutic effect on glaucoma, the surgical success rate of patients is higher than trabeculectomy, the postoperative intraocular pressure of patients is significantly reduced, and the surgical safety is worthy of affirmation. [ABSTRACT FROM AUTHOR]