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Immune checkpoint blockade provokes resident memory T cells to eliminate head and neck cancer.

Authors :
Veatch, Joshua R.
Riddell, Stanley R.
Source :
Cell. Aug2022, Vol. 185 Issue 16, p2848-2849. 2p.
Publication Year :
2022

Abstract

Immune checkpoint blockade is effective in treating many human cancers. In this issue of Cell , Luoma et al. show that tissue-resident memory T cells in head and neck cancers rapidly respond to immune checkpoint blockade, and they identify specific CD8+ T cells in pretreatment blood that predict pathologic tumor regression. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00928674
Volume :
185
Issue :
16
Database :
Academic Search Index
Journal :
Cell
Publication Type :
Academic Journal
Accession number :
158368205
Full Text :
https://doi.org/10.1016/j.cell.2022.07.006