Distribution of Serogroup and Antibiotic Resistance Patterns of Shigella Species in Iran, 1984- 2018: A systematic Review.

Background: Shigellosis is recognized as a global concern by the WHO. Shigella genus includes 4 species of Shigella dysenteriae, Shigella flexneri, Shigella boydii and Shigella sonnei. Geographic distribution and antimicrobial susceptibility patterns of Shigella species are different. Methods: We searched published studies in Science Direct, PubMed, PubMed Central (PMC), Scopus, Google Scholar, and ISI Web of Science, Medlib, Magiran, Iranian Scientific Information Database (SID) and 'IranMedex between 1984 and 2018. Results: Many studies in Iran and elsewhere in the world emphasize the emergence of Shigella resistant species. Most of them have shown high resistance to TMP/STX, tetracycline, ampicillin and streptomycin, and some have resistance to antibiotics such as ciprofloxacin, azithromycin, and tetracyclines have reported. Conclusions: The frequency of Shigella species is very different in different countries. The distribution and prevalence of Shigella species in different countries may depend on the level of economic development, age, and environmental factors. [ABSTRACT FROM AUTHOR]