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PPh3‐Mediated Wittig‐Like/Mannich Tandem Reactions of 2‐Alkynylnitrobenzenes with Ketones for the Synthesis of 2,2‐Disubstituted Indolin‐3‐Ones.
- Source :
-
Advanced Synthesis & Catalysis . 7/19/2022, Vol. 364 Issue 14, p2358-2363. 6p. - Publication Year :
- 2022
-
Abstract
- A synthetic strategy for the construction of 2,2‐disubstituted indolin‐3‐ones from 2‐alkynylnitroarenes and ketones has been described. The corresponding indolin‐3‐one derivatives were afforded in moderate to excellent product yields by using mild conditions. After a Wittig‐like process, the key intermediates 3H‐indol‐3‐ones were generated from 2‐alkynylnitroarenes, which could be further transformed to the desired products through a Mannich addition. [ABSTRACT FROM AUTHOR]
- Subjects :
- *KETONES
Subjects
Details
- Language :
- English
- ISSN :
- 16154150
- Volume :
- 364
- Issue :
- 14
- Database :
- Academic Search Index
- Journal :
- Advanced Synthesis & Catalysis
- Publication Type :
- Academic Journal
- Accession number :
- 158067012
- Full Text :
- https://doi.org/10.1002/adsc.202200323