A fertility-sparing alternative to radical hysterectomy: how many patients may be eligible?

Abstract: Objective.: To determine the percentage of patients with early-stage cervical cancer who may be eligible for fertility preservation with laparoscopic radical vaginal trachelectomy (LRVT). Methods.: We retrospectively reviewed the records of patients who underwent a radical hysterectomy for invasive cervical cancer at our institution from 12/85 to 8/01, before our use of LRVT at Memorial Sloan-Kettering Cancer Center. Institutional eligibility criteria for LRVT were applied. Patients ≥40 years of age were considered ineligible. Results.: We identified 435 patients who had undergone radical hysterectomy for cervical cancer; 186 were age <40 at surgery and constituted our study population. Eighty-nine (48%) patients may have been eligible by our pathologic criteria. In 12 patients, LRVT may have been aborted or altered because of unexpected disease spread. Conclusion.: A significant number of patients <40 with early-stage cervical cancer may be pathologically eligible for LRVT and should be counseled on this preoperatively. [Copyright &y& Elsevier]