Bioactive Terpenoid from the Fruits of Lagerstroemia speciosa and its Molecular Docking Study.

Bioactive terpenoids 1 and 2 along with a known compound, β-sitosterol, have been isolated from the DCM extract of the fruits of Lagerstroemia speciosa. Structures of 1 and 2 have been established by spectroscopic analysis. In vitro antibacterial and antifungal activity of 1 and 2 have been reported. Compound 1 showed poor activity, but compound 2 exhibited significant antibacterial and antifungal activities. Molecular docking study of 2 also showed a good docking score within the binding pocket of the selected proteins. [ABSTRACT FROM AUTHOR]